4F2C
The Crystal Structure of a Human MitoNEET double mutant in which Gly 66 are Asp 67 are both Replaced with Ala Residues
Summary for 4F2C
Entry DOI | 10.2210/pdb4f2c/pdb |
Related | 2QH7 3EW0 3LPQ 4EZF 4F1E 4F28 |
Descriptor | CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER (3 entities in total) |
Functional Keywords | mitochondrial outer membrane, signal-anchor, transmembrane metal binding protein, protein frustration, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion outer membrane; Single-pass type III membrane protein: Q9NZ45 |
Total number of polymer chains | 2 |
Total formula weight | 18188.33 |
Authors | Baxter, E.L.,Zuris, J.A.,Wang, C.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. (deposition date: 2012-05-07, release date: 2012-12-26, Last modification date: 2023-09-13) |
Primary citation | Baxter, E.L.,Zuris, J.A.,Wang, C.,Vo, P.L.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. Allosteric control in a metalloprotein dramatically alters function. Proc.Natl.Acad.Sci.USA, 110:948-953, 2013 Cited by PubMed: 23271805DOI: 10.1073/pnas.1208286110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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