4F12

Crystal structure of the extracellular domain of human GABA(B) receptor GBR2

Summary for 4F12

• Entry DOI: 10.2210/pdb4f12/pdb
• Related: 4F11
• Descriptor: Gamma-aminobutyric acid type B receptor subunit 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: venus flytrap module, g-protein coupled receptor, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 50361.66

Authors

Geng, Y.,Xiong, D.,Mosyak, L.,Malito, D.L.,Kniazeff, J.,Chen, Y.,Burmakina, S.,Quick, M.,Bush, M.,Javitch, J.A.,Pin, J.-P.,Fan, Q.R. (deposition date: 2012-05-05, release date: 2012-06-06, Last modification date: 2020-07-29)

• Primary citation: Geng, Y.,Xiong, D.,Mosyak, L.,Malito, D.L.,Kniazeff, J.,Chen, Y.,Burmakina, S.,Quick, M.,Bush, M.,Javitch, J.A.,Pin, J.P.,Fan, Q.R.; Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.; Nat.Neurosci., 15:970-978, 2012; PubMed: 22660477; DOI: 10.1038/nn.3133

Experimental method

X-RAY DIFFRACTION (3.02 Å)