4EWI

Crystal structure of the NLRP4 Pyrin domain

Summary for 4EWI

• Entry DOI: 10.2210/pdb4ewi/pdb
• Descriptor: NACHT, LRR and PYD domains-containing protein 4, CHLORIDE ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: nlr proteins, death domain, pyrin domain, nlrp4, asc, innate immune system, inflammasome, apoptosis, protein-protein interaction, signaling protein, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 27785.20

Authors

Eibl, C.,Hessenberger, M.,Puehringer, S.,Page, R.,Diederichs, K.,Peti, W. (deposition date: 2012-04-27, release date: 2012-09-05, Last modification date: 2024-02-28)

• Primary citation: Eibl, C.,Grigoriu, S.,Hessenberger, M.,Wenger, J.,Puehringer, S.,Pinheiro, A.S.,Wagner, R.N.,Proell, M.,Reed, J.C.,Page, R.,Diederichs, K.,Peti, W.; Structural and Functional Analysis of the NLRP4 Pyrin Domain.; Biochemistry, 51:7330-7341, 2012; PubMed: 22928810; DOI: 10.1021/bi3007059

Experimental method

X-RAY DIFFRACTION (2.28 Å)