4ELU

Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines

Summary for 4ELU

• Entry DOI: 10.2210/pdb4elu/pdb
• Related: 3OJS 3OJU 4ELT 4ELV
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), DNA (5'-D(*AP*AP*AP*GP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (9 entities in total)
• Functional Keywords: dna polymerase, modified nucleotides, a family, dna synthesis, rigid linker, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 3
• Total formula weight: 71732.32

Authors

Marx, A.,Diederichs, K.,Obeid, S. (deposition date: 2012-04-11, release date: 2013-03-27, Last modification date: 2023-09-13)

• Primary citation: Obeid, S.,Busskamp, H.,Welte, W.,Diederichs, K.,Marx, A.; Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site.; Chem.Commun.(Camb.), 48:8320-8322, 2012; PubMed: 22766607; DOI: 10.1039/c2cc34181f

Experimental method

X-RAY DIFFRACTION (1.8 Å)