Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4ELB

Structure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductase

Summary for 4ELB
Entry DOI10.2210/pdb4elb/pdb
Related3ELE 3ELF 3FL8 3FL9 4ELG 4ELH
DescriptorDihydrofolate reductase, CALCIUM ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsdihydrofolate reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceBacillus anthracis (anthrax,anthrax bacterium)
Total number of polymer chains8
Total formula weight162733.69
Authors
Bourne, C.R.,Barrow, W.W. (deposition date: 2012-04-10, release date: 2013-02-13, Last modification date: 2023-09-13)
Primary citationBourne, C.R.,Wakeham, N.,Nammalwar, B.,Tseitin, V.,Bourne, P.C.,Barrow, E.W.,Mylvaganam, S.,Ramnarayan, K.,Bunce, R.A.,Berlin, K.D.,Barrow, W.W.
Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase.
Biochim.Biophys.Acta, 1834:46-52, 2013
Cited by
PubMed: 22999981
DOI: 10.1016/j.bbapap.2012.09.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon