4EKD

Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)

Summary for 4EKD

• Entry DOI: 10.2210/pdb4ekd/pdb
• Related: 1AGR 2AF0 2BCJ 2V4Z 4EKC
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 2, GUANOSINE-5'-DIPHOSPHATE, ... (9 entities in total)
• Functional Keywords: gtp-binding, regulator of g protein signaling, homology domain, gtpase activation, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 57460.50

Authors

Tesmer, J.J.G.,Nance, M.R. (deposition date: 2012-04-09, release date: 2013-01-30, Last modification date: 2023-09-13)

• Primary citation: Nance, M.R.,Kreutz, B.,Tesmer, V.M.,Sterne-Marr, R.,Kozasa, T.,Tesmer, J.J.; Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.; Structure, 21:438-448, 2013; PubMed: 23434405; DOI: 10.1016/j.str.2012.12.016

Experimental method

X-RAY DIFFRACTION (2.71 Å)