4E3T
Round 18 Arylesterase Variant of Phosphotriesterase with Bound Transition State Analog
Summary for 4E3T
| Entry DOI | 10.2210/pdb4e3t/pdb |
| Descriptor | Phosphotriesterase, ZINC ION, hexyl(naphthalen-2-yloxy)phosphinic acid, ... (4 entities in total) |
| Functional Keywords | phosphotriesterase, alpha/beta hydrolase, arylesterase, hydrolase |
| Biological source | Brevundimonas diminuta |
| Total number of polymer chains | 2 |
| Total formula weight | 73101.59 |
| Authors | Tokuriki, N.,Jackson, C.J.,Tawfik, D.S. (deposition date: 2012-03-10, release date: 2013-01-23, Last modification date: 2023-11-08) |
| Primary citation | Tokuriki, N.,Jackson, C.J.,Afriat-Jurnou, L.,Wyganowski, K.T.,Tang, R.,Tawfik, D.S. Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3:1257-1257, 2012 Cited by PubMed: 23212386DOI: 10.1038/ncomms2246 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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