4E2V

tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1

Summary for 4E2V

• Entry DOI: 10.2210/pdb4e2v/pdb
• Related: 2NQZ 2NSO 3BL3 3BLD 3BLL 3BLO
• Descriptor: Queuine tRNA-ribosyltransferase, 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: substrate specificity, bacterial tgt, guanin, trna, preq1, guanine exchange enzyme, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43518.65

Authors

Schmidt, I.,Reuter, K.,Klebe, G.,Heine, A.,Tidten, N. (deposition date: 2012-03-09, release date: 2013-03-27, Last modification date: 2023-09-13)

• Primary citation: Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K.; Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor.; Plos One, 8:e64240-e64240, 2013; PubMed: 23704982; DOI: 10.1371/journal.pone.0064240

Experimental method

X-RAY DIFFRACTION (1.18 Å)