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4DVV

Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AS-I-261

Summary for 4DVV
Entry DOI10.2210/pdb4dvv/pdb
Related4DVR 4DVS 4DVT 4DVU 4DVW 4DVX
Descriptorclade A/E 93TH057 HIV-1 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywordshiv-1 gp120, small molecule inhibitor, cd4 binding site, as-i-261, viral protein-transcription inhibitor complex, viral protein/transcription inhibitor
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight84383.48
Authors
Kwon, Y.D.,Kwong, P.D. (deposition date: 2012-02-23, release date: 2013-02-27, Last modification date: 2023-09-13)
Primary citationKwon, Y.D.,Lalonde, J.M.,Yang, Y.,Elban, M.A.,Sugawara, A.,Courter, J.R.,Jones, D.M.,Smith, A.B.,Debnath, A.K.,Kwong, P.D.
Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9:e85940-e85940, 2014
Cited by
PubMed: 24489681
DOI: 10.1371/journal.pone.0085940
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.94 Å)
Structure validation

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