4DVH

Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase

Summary for 4DVH

Entry DOI	10.2210/pdb4dvh/pdb
Descriptor	Superoxide dismutase, FE (III) ION (3 entities in total)
Functional Keywords	iron superoxide dismutase, mitochondrial, oxidoreductase
Biological source	Trypanosoma cruzi
Total number of polymer chains	2
Total formula weight	47337.08
Authors	Larrieux, N.,Buschiazzo, A. (deposition date: 2012-02-23, release date: 2013-03-27, Last modification date: 2023-09-13)
Primary citation	Martinez, A.,Peluffo, G.,Petruk, A.A.,Hugo, M.,Pineyro, D.,Demicheli, V.,Moreno, D.M.,Lima, A.,Batthyany, C.,Duran, R.,Robello, C.,Marti, M.A.,Larrieux, N.,Buschiazzo, A.,Trujillo, M.,Radi, R.,Piacenza, L. Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B: DISPARATE SUSCEPTIBILITIES DUE TO THE REPAIR OF TYR35 RADICAL BY CYS83 IN Fe-SODB THROUGH INTRAMOLECULAR ELECTRON TRANSFER. J.Biol.Chem., 289:12760-12778, 2014 Cited by PubMed: 24616096 DOI: 10.1074/jbc.M113.545590 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation