4DRW

Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide

Summary for 4DRW

Entry DOI	10.2210/pdb4drw/pdb
Descriptor	Protein S100-A10/Annexin A2 chimeric protein, Neuroblast differentiation-associated protein AHNAK (2 entities in total)
Functional Keywords	atypical ef-hand, heteropentameric complex, membrane repair, exocytosis-protein binding complex, exocytosis/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space, extracellular matrix, basement membrane : P07355 Nucleus: Q09666
Total number of polymer chains	6
Total formula weight	59696.76
Authors	Rezvanpour, A.,Lee, T.-W.,Junop, M.S.,Shaw, G.S. (deposition date: 2012-02-17, release date: 2012-10-24, Last modification date: 2023-09-13)
Primary citation	Dempsey, B.R.,Rezvanpour, A.,Lee, T.W.,Barber, K.R.,Junop, M.S.,Shaw, G.S. Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure, 20:1737-1745, 2012 Cited by PubMed: 22940583 DOI: 10.1016/j.str.2012.08.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation