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4DR4

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound

Summary for 4DR4
Entry DOI10.2210/pdb4dr4/pdb
Related4DR1 4DR2 4DR3 4DR5 4DR6 4DR7
Descriptor16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (27 entities in total)
Functional Keywordsdecoding, streptomycin, rna structure, antibiotic resistance, ribosome-antibiotic complex, ribosome/antibiotic
Biological sourceThermus thermophilus
More
Total number of polymer chains23
Total formula weight809514.08
Authors
Demirci, H.,Murphy IV, F.,Murphy, E.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. (deposition date: 2012-02-16, release date: 2012-11-14, Last modification date: 2013-01-30)
Primary citationDemirci, H.,Murphy, F.,Murphy, E.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G.
A structural basis for streptomycin-induced misreading of the genetic code.
Nat Commun, 4:1355-1355, 2013
Cited by
PubMed: 23322043
DOI: 10.1038/ncomms2346
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.969 Å)
Structure validation

217705

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