4DN8

Structure of porcine surfactant protein D neck and carbohydrate recognition domain complexed with mannose

Summary for 4DN8

Entry DOI	10.2210/pdb4dn8/pdb
Descriptor	Pulmonary surfactant-associated protein D, CALCIUM ION, beta-D-mannopyranose, ... (4 entities in total)
Functional Keywords	collectin, lectin, carbohydrate/sugar binding, lung surfactant, sugar binding protein
Biological source	Sus scrofa (pigs,swine,wild boar)
Total number of polymer chains	1
Total formula weight	17318.31
Authors	van Eijk, M.,Rynkiewicz, M.J.,White, M.R.,Hartshorn, K.L.,Zou, X.,Schulten, K.,Luo, D.,Crouch, E.C.,Cafarella, T.M.,Head, J.F.,Haagsman, H.P.,Seaton, B.A. (deposition date: 2012-02-08, release date: 2012-06-20, Last modification date: 2023-09-13)
Primary citation	van Eijk, M.,Rynkiewicz, M.J.,White, M.R.,Hartshorn, K.L.,Zou, X.,Schulten, K.,Luo, D.,Crouch, E.C.,Cafarella, T.R.,Head, J.F.,Haagsman, H.P.,Seaton, B.A. A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D. J.Biol.Chem., 287:26666-26677, 2012 Cited by PubMed: 22685299 DOI: 10.1074/jbc.M112.368571 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation