4DKY

Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra]

Summary for 4DKY

Entry DOI	10.2210/pdb4dky/pdb
Related	3C4I
Descriptor	DNA-binding protein HU homolog, MANGANESE (II) ION (3 entities in total)
Functional Keywords	nucleoid associated protein, nucleoid architecture, histone-like, hu, hu-ihf fold, genome compaction, gene regulation, dna binding protein
Biological source	Mycobacterium tuberculosis H37Ra
Total number of polymer chains	2
Total formula weight	23306.30
Authors	Bhowmick, T.,Ramagopal, U.A.,Ghosh, S.,Nagaraja, V.,Ramakumar, S. (deposition date: 2012-02-05, release date: 2013-02-06, Last modification date: 2023-11-08)
Primary citation	Bhowmick, T.,Ghosh, S.,Dixit, K.,Ganesan, V.,Ramagopal, U.A.,Dey, D.,Sarma, S.P.,Ramakumar, S.,Nagaraja, V. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors Nat Commun, 5:4124-4124, 2014 Cited by PubMed: 24916461 DOI: 10.1038/ncomms5124 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.478 Å)

Structure validation