4DG0

Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP

Summary for 4DG0

Entry DOI	10.2210/pdb4dg0/pdb
Related	1ATP 1CTP 1JBP 4DFX 4DFZ 4DG2
Descriptor	cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MYRISTIC ACID, ... (6 entities in total)
Functional Keywords	protein kinase, myristoylated, phosphotransferase of ser/thr, mg, pki, pka regulatory subunits, phosphorylated on s139, t197, s338, myristoylated on g1, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Mus musculus (mouse) More
Cellular location	Cytoplasm: P05132
Total number of polymer chains	2
Total formula weight	43719.86
Authors	Bastidas, A.C.,Steichen, J.M.,Taylor, S.S. (deposition date: 2012-01-24, release date: 2012-06-06, Last modification date: 2013-01-02)
Primary citation	Bastidas, A.C.,Deal, M.S.,Steichen, J.M.,Keshwani, M.M.,Guo, Y.,Taylor, S.S. Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422:215-229, 2012 Cited by PubMed: 22617327 DOI: 10.1016/j.jmb.2012.05.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation