4DFY
Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop
Summary for 4DFY
| Entry DOI | 10.2210/pdb4dfy/pdb |
| Related | 1ATP 1J3H |
| Descriptor | cAMP-dependent protein kinase catalytic subunit alpha (2 entities in total) |
| Functional Keywords | protein kinase fold, serine/threonine kinase activity, camp-dependent protein kinase regulatory subunit, pki, phosphorylation, transferase |
| Biological source | Mus musculus (mouse) |
| Cellular location | Cytoplasm: P05132 |
| Total number of polymer chains | 2 |
| Total formula weight | 85587.53 |
| Authors | Steichen, J.M.,Kuchinskas, M.,Yang, J.,Taylor, S.S. (deposition date: 2012-01-24, release date: 2012-02-15, Last modification date: 2023-09-13) |
| Primary citation | Steichen, J.M.,Kuchinskas, M.,Keshwani, M.M.,Yang, J.,Adams, J.A.,Taylor, S.S. Structural basis for the regulation of protein kinase a by activation loop phosphorylation. J.Biol.Chem., 287:14672-14680, 2012 Cited by PubMed: 22334660DOI: 10.1074/jbc.M111.335091 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.997 Å) |
Structure validation
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