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4DER

Crystal Structure of the Wild Type TTR Binding Apigenin (TTRwt:API)

Summary for 4DER
Entry DOI10.2210/pdb4der/pdb
Related3KGS 3KGT 3KGU 3NEE 3NEO 3NES 4DES 4DET 4DEU 4DEW
DescriptorTransthyretin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, GLYCEROL, ... (4 entities in total)
Functional Keywordsbeta sandwich, amyloidosis, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight26039.00
Authors
Trivella, D.B.B.,Polikarpov, I. (deposition date: 2012-01-21, release date: 2012-11-21, Last modification date: 2023-09-13)
Primary citationTrivella, D.B.,Dos Reis, C.V.,Lima, L.M.,Foguel, D.,Polikarpov, I.
Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180:143-153, 2012
Cited by
PubMed: 22842046
DOI: 10.1016/j.jsb.2012.07.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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