4DEQ
Structure of the Neuropilin-1/VEGF-A complex
Summary for 4DEQ
| Entry DOI | 10.2210/pdb4deq/pdb |
| Descriptor | Neuropilin-1, Vascular endothelial growth factor A, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | coagulation factor domain, heparin binding domain, angiogenesis, protein binding-cytokine complex, protein binding/cytokine |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted : P15692 |
| Total number of polymer chains | 2 |
| Total formula weight | 49416.83 |
| Authors | Vander Kooi, C.W. (deposition date: 2012-01-21, release date: 2012-02-08, Last modification date: 2023-09-13) |
| Primary citation | Parker, M.W.,Xu, P.,Li, X.,Vander Kooi, C.W. Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1. J.Biol.Chem., 287:11082-11089, 2012 Cited by PubMed: 22318724DOI: 10.1074/jbc.M111.331140 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.649 Å) |
Structure validation
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