4D1X
CDK2 in complex with Luciferin
Summary for 4D1X
Entry DOI | 10.2210/pdb4d1x/pdb |
Related | 4D1Z |
Descriptor | CYCLIN-DEPENDENT KINASE 2, (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid (3 entities in total) |
Functional Keywords | transferase, kinase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 |
Total number of polymer chains | 1 |
Total formula weight | 34256.81 |
Authors | Rothweiler, U.,Engh, R.A. (deposition date: 2014-05-05, release date: 2015-03-18, Last modification date: 2023-12-20) |
Primary citation | Rothweiler, U.,Eriksson, J.,Stensen, W.,Leeson, F.,Engh, R.A.,Svendsen, J.S. Luciferin and Derivatives as a Dyrk Selective Scaffold for the Design of Protein Kinase Inhibitors. Eur.J.Med.Chem., 94:140-, 2015 Cited by PubMed: 25768698DOI: 10.1016/J.EJMECH.2015.02.035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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