4D1P
Structure of human endothelial nitric oxide synthase heme domain IN COMPLEX WITH 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2-YL)METHOXY) METHYL)PYRROLIDIN-3-YL)OXY) METHYL)-4-METHYLPYRIDIN-2-AMINE
Summary for 4D1P
Entry DOI | 10.2210/pdb4d1p/pdb |
Related | 4D1N 4D1O |
Descriptor | NITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total) |
Functional Keywords | oxidoreductase, nitric oxide synthase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane: P29474 |
Total number of polymer chains | 2 |
Total formula weight | 102667.05 |
Authors | Li, H.,Poulos, T.L. (deposition date: 2014-05-02, release date: 2014-10-15, Last modification date: 2023-12-20) |
Primary citation | Li, H.,Jamal, J.,Plaza, C.,Pineda, S.H.,Chreifi, G.,Jing, Q.,Cinelli, M.A.,Silverman, R.B.,Poulos, T.L. Structures of Human Constitutive Nitric Oxide Synthases Acta Crystallogr.,Sect.D, 70:2667-, 2014 Cited by PubMed: 25286850DOI: 10.1107/S1399004714017064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.731 Å) |
Structure validation
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