4CZY
Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term)
Summary for 4CZY
Entry DOI | 10.2210/pdb4czy/pdb |
Related | 4CZV 4CZW 4CZX 4D0K |
Descriptor | PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | gene regulation, wd40 domain, pseudokinase, c-terminal knob domain, deadenylation, mrna decay, pan2-pan3 complex |
Biological source | NEUROSPORA CRASSA More |
Cellular location | Cytoplasm (By similarity): P0C581 Q7SDP4 |
Total number of polymer chains | 4 |
Total formula weight | 179029.75 |
Authors | Jonas, S.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-04-22, release date: 2014-06-04, Last modification date: 2023-12-20) |
Primary citation | Jonas, S.,Christie, M.,Peter, D.,Bhandari, D.,Loh, B.,Huntzinger, E.,Weichenrieder, O.,Izaurralde, E. An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21:599-, 2014 Cited by PubMed: 24880343DOI: 10.1038/NSMB.2837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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