4CZY

Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term)

Summary for 4CZY

Entry DOI	10.2210/pdb4czy/pdb
Related	4CZV 4CZW 4CZX 4D0K
Descriptor	PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	gene regulation, wd40 domain, pseudokinase, c-terminal knob domain, deadenylation, mrna decay, pan2-pan3 complex
Biological source	NEUROSPORA CRASSA More
Cellular location	Cytoplasm (By similarity): P0C581 Q7SDP4
Total number of polymer chains	4
Total formula weight	179029.75
Authors	Jonas, S.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-04-22, release date: 2014-06-04, Last modification date: 2023-12-20)
Primary citation	Jonas, S.,Christie, M.,Peter, D.,Bhandari, D.,Loh, B.,Huntzinger, E.,Weichenrieder, O.,Izaurralde, E. An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21:599-, 2014 Cited by PubMed: 24880343 DOI: 10.1038/NSMB.2837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation