4CZW

Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain)

Summary for 4CZW

Entry DOI	10.2210/pdb4czw/pdb
Related	4CZV 4CZX 4CZY 4D0K
Descriptor	PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ZINC ION (3 entities in total)
Functional Keywords	gene regulation, deed exoribonuclease, ubiquitin specific protease, deadenylation, mrna decay, pan2-pan3 complex
Biological source	NEUROSPORA CRASSA
Cellular location	Cytoplasm (By similarity): P0C581
Total number of polymer chains	1
Total formula weight	75068.56
Authors	Christie, M.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-04-22, release date: 2014-06-04, Last modification date: 2014-07-16)
Primary citation	Jonas, S.,Christie, M.,Peter, D.,Bhandari, D.,Loh, B.,Huntzinger, E.,Weichenrieder, O.,Izaurralde, E. An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21:599-, 2014 Cited by PubMed: 24880343 DOI: 10.1038/NSMB.2837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation