4CS2

Catalytic domain of Pyrrolysyl-tRNA synthetase mutant Y306A, Y384F in its apo form

Summary for 4CS2

Entry DOI	10.2210/pdb4cs2/pdb
Descriptor	PYRROLYSINE--TRNA LIGASE, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	ligase
Biological source	METHANOSARCINA MAZEI
Cellular location	Cytoplasm (By similarity): Q8PWY1
Total number of polymer chains	1
Total formula weight	32090.80
Authors	Schmidt, M.J.,Weber, A.,Pott, M.,Welte, W.,Summerer, D. (deposition date: 2014-03-04, release date: 2014-04-30, Last modification date: 2023-12-20)
Primary citation	Schmidt, M.J.,Weber, A.,Pott, M.,Welte, W.,Summerer, D. Structural Basis of Furan-Amino Acid Recognition by a Polyspecific Aminoacyl-tRNA-Synthetase and its Genetic Encoding in Human Cells. Chembiochem, 15:1755-, 2014 Cited by PubMed: 24737732 DOI: 10.1002/CBIC.201402006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation