4CRW

Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G)

Summary for 4CRW

Entry DOI	10.2210/pdb4crw/pdb
Related	2WAX 2WAY 4GMJ 4GML
Descriptor	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6, GLYCEROL, ... (4 entities in total)
Functional Keywords	gene regulation, ccr4-not, translational repression, mrna decapping, dead-box protein, p54, rck, helicase, mrna silencing, mrna deadenylation, eif4a, translation, mirna, p-bodies
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, P-body: A5YKK6 P26196
Total number of polymer chains	2
Total formula weight	48553.90
Authors	Chen, Y.,Boland, A.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-03-01, release date: 2014-05-07, Last modification date: 2023-12-20)
Primary citation	Chen, Y.,Boland, A.,Kuzuoglu-Ozturk, D.,Bawankar, P.,Loh, B.,Chang, C.T.,Weichenrieder, O.,Izaurralde, E. A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54:737-, 2014 Cited by PubMed: 24768540 DOI: 10.1016/J.MOLCEL.2014.03.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation