4CHL

Human Ethylmalonic Encephalopathy Protein 1 (hETHE1)

Summary for 4CHL

Entry DOI	10.2210/pdb4chl/pdb
Descriptor	PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL, FE (III) ION (3 entities in total)
Functional Keywords	oxidoreductase, sulfide detoxification, glyoxalase ii family
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : O95571
Total number of polymer chains	2
Total formula weight	52469.42
Authors	Pettinati, I.,Brem, J.,McDonough, M.A.,Schofield, C.J. (deposition date: 2013-12-03, release date: 2014-12-17, Last modification date: 2023-12-20)
Primary citation	Pettinati, I.,Brem, J.,McDonough, M.A.,Schofield, C.J. Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy. Hum. Mol. Genet., 24:2458-2469, 2015 Cited by PubMed: 25596185 DOI: 10.1093/hmg/ddv007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation