4CCD

STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH D-GALACTAL: ENZYME- INTERMEDIATE COMPLEX

Summary for 4CCD

Entry DOI	10.2210/pdb4ccd/pdb
Related	4CCC 4CCE
Descriptor	GALACTOCEREBROSIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-alpha-D-galactopyranose, ... (6 entities in total)
Functional Keywords	hydrolase, krabbe disease, glycosyl hydrolase, galactosidase, d-galactal, lysosomal storage disease, enzyme-intermediate complex
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Lysosome (By similarity): P54818
Total number of polymer chains	1
Total formula weight	76295.39
Authors	Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E. (deposition date: 2013-10-21, release date: 2013-12-11, Last modification date: 2023-12-20)
Primary citation	Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E. Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease Proc.Natl.Acad.Sci.USA, 110:20479-, 2013 Cited by PubMed: 24297913 DOI: 10.1073/PNAS.1311990110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation