4CBZ

Notch ligand, Jagged-1, contains an N-terminal C2 domain

Summary for 4CBZ

Entry DOI	10.2210/pdb4cbz/pdb
Related	4CC0 4CC1
Descriptor	PROTEIN JAGGED-1, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose, ... (4 entities in total)
Functional Keywords	signaling protein, signalling, glycoprotein, extracellular, developmental protein, notch signaling pathway, egf-like domain transmembrane, egf-like domain, disease mutation
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	70234.07
Authors	Chilakuri, C.R.,Sheppard, D.,Ilagan, M.X.G.,Holt, L.R.,Abbott, F.,Liang, S.,Kopan, R.,Handford, P.A.,Lea, S.M. (deposition date: 2013-10-17, release date: 2013-11-27, Last modification date: 2023-12-20)
Primary citation	Chilakuri, C.R.,Sheppard, D.,Ilagan, M.X.G.,Holt, L.R.,Abbott, F.,Liang, S.,Kopan, R.,Handford, P.A.,Lea, S.M. Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5:861-, 2013 Cited by PubMed: 24239355 DOI: 10.1016/J.CELREP.2013.10.029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation