4C8O

Binary complex of the large fragment of DNA polymerase I from Thermus Aquaticus with the aritificial base pair dNaM-d5SICS at the postinsertion site (sequence context 2)

Summary for 4C8O

• Entry DOI: 10.2210/pdb4c8o/pdb
• Related: 4C8J 4C8K 4C8L 4C8M 4C8N
• Descriptor: DNA POLYMERASE I, THERMOSTABLE, 5'-D(*GP*CP*CP*AP*CP*GP*GP*CP*GP*CP*LHOP)-3', 5'-D(*TP*TP*CP*BMNP*GP*CP*GP*CP*CP*GP*TP*GP*GP*CP)-3', ... (8 entities in total)
• Functional Keywords: transferase-dna complex, dna polymerase, unnatural base pair, artificial base pair, binary complex, klentaq, transferase/dna
• Biological source: THERMUS AQUATICUS; More
• Total number of polymer chains: 3
• Total formula weight: 69471.45

Authors

Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. (deposition date: 2013-10-01, release date: 2013-12-11, Last modification date: 2017-08-23)

• Primary citation: Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A.; Structural Insights Into DNA Replication without Hydrogen Bonds.; J.Am.Chem.Soc., 135:18637-, 2013; PubMed: 24283923; DOI: 10.1021/JA409609J

Experimental method

X-RAY DIFFRACTION (1.75 Å)