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4C2S

Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor

Summary for 4C2S
Entry DOI10.2210/pdb4c2s/pdb
DescriptorHISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywordsgta, abo, blood group antigen, glycosylation, transferase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
Total number of polymer chains2
Total formula weight69833.85
Authors
Weadge, J.T.,Palcic, M.,Henriksen, A. (deposition date: 2013-08-19, release date: 2013-09-11, Last modification date: 2023-12-20)
Primary citationWeadge, J.T.,Palcic, M.,Henriksen, A.
Structural and Biochemical Characterization of the Human Blood Group a and B Galactosyltransferases Posessing the Pro156Leu Mutation
To be Published,
Experimental method
X-RAY DIFFRACTION (2.48 Å)
Structure validation

217705

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