4BUO

High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion

Summary for 4BUO

Entry DOI	10.2210/pdb4buo/pdb
Related	3ZEV 4BV0 4BWB
Descriptor	NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N, GLYCINE (3 entities in total)
Functional Keywords	signaling protein, g protein coupled receptor, membrane protein
Biological source	RATTUS NORVEGICUS (NORWAY RAT) More
Cellular location	Cell membrane; Multi-pass membrane protein: P20789 Secreted: P20068
Total number of polymer chains	4
Total formula weight	77764.14
Authors	Egloff, P.,Hillenbrand, M.,Schlinkmann, K.M.,Batyuk, A.,Mittl, P.,Plueckthun, A. (deposition date: 2013-06-21, release date: 2014-01-29, Last modification date: 2023-12-20)
Primary citation	Egloff, P.,Hillenbrand, M.,Klenk, C.,Batyuk, A.,Heine, P.,Balada, S.,Schlinkmann, K.M.,Scott, D.J.,Schuetz, M.,Plueckthun, A. Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli Proc.Natl.Acad.Sci.USA, 111:E655-, 2014 Cited by PubMed: 24453215 DOI: 10.1073/PNAS.1317903111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation