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4BSS

Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form

Summary for 4BSS
Entry DOI10.2210/pdb4bss/pdb
Related4BSO 4BSP 4BSR 4BST 4BSU
DescriptorLEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordssignaling protein, adult stem cell, leucine-rich repeat g-protein coupled receptor, leucine-rich repeat, furin domain, wnt signaling, congenital anonychia
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains8
Total formula weight298875.38
Authors
Peng, W.C.,de Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P. (deposition date: 2013-06-11, release date: 2013-06-19, Last modification date: 2020-07-29)
Primary citationPeng, W.C.,De Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P.
Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3:1885-, 2013
Cited by
PubMed: 23809763
DOI: 10.1016/J.CELREP.2013.06.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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