4BPX
Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha
Summary for 4BPX
| Entry DOI | 10.2210/pdb4bpx/pdb |
| Related | 4BPU 4BPW |
| Descriptor | DNA PRIMASE SMALL SUBUNIT, DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, ZINC ION (3 entities in total) |
| Functional Keywords | transferase, dna replication, fusion protein, chimera |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Total number of polymer chains | 4 |
| Total formula weight | 161894.97 |
| Authors | Kilkenny, M.L.,Perera, R.L.,Pellegrini, L. (deposition date: 2013-05-28, release date: 2013-09-25, Last modification date: 2023-12-20) |
| Primary citation | Kilkenny, M.L.,Longo, M.,Perera, R.L.,Pellegrini, L. Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110:15961-, 2013 Cited by PubMed: 24043831DOI: 10.1073/PNAS.1311185110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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