4BME

Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant

Summary for 4BME

• Entry DOI: 10.2210/pdb4bme/pdb
• Related: 4BMB
• Related PRD ID: PRD_900008
• Descriptor: GALECTIN-8, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: sugar binding protein, carbohydrate recognition
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm (Probable): O00214
• Total number of polymer chains: 2
• Total formula weight: 35050.03

Authors

Buzamet, E.,Ruiz, F.M.,Menendez, M.,Romero, A.,Gabius, H.J.,Solis, D. (deposition date: 2013-05-07, release date: 2014-03-19, Last modification date: 2023-12-20)

• Primary citation: Ruiz, F.M.,Scholz, B.A.,Buzamet, E.,Kopitz, J.,Andre, S.,Menendez, M.,Romero, A.,Solis, D.,Gabius, H.J.; Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells.; FEBS J., 281:1446-, 2014; PubMed: 24418318; DOI: 10.1111/FEBS.12716

Experimental method

X-RAY DIFFRACTION (2 Å)