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4BJB

Crystal structure of human tankyrase 2 in complex with PJ-34

Summary for 4BJB
Entry DOI10.2210/pdb4bjb/pdb
Related4BJ9
DescriptorTANKYRASE-2, SULFATE ION, GLYCEROL, ... (6 entities in total)
Functional Keywordstransferase, diphtheria toxin like fold, adp- ribosylation, inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm: Q9H2K2
Total number of polymer chains1
Total formula weight27944.73
Authors
Haikarainen, T.,Narwal, M.,Lehtio, L. (deposition date: 2013-04-17, release date: 2013-12-11, Last modification date: 2014-06-18)
Primary citationHaikarainen, T.,Narwal, M.,Joensuu, P.,Lehtio, L.
Evaluation and Structural Basis for the Inhibition of Tankyrases by Parp Inhibitors.
Acs Med.Chem.Lett., 5:18-, 2014
Cited by
PubMed: 24900770
DOI: 10.1021/ML400292S
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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