4B9L
Structure of the high fidelity DNA polymerase I with the oxidative formamidopyrimidine-dA DNA lesion in the pre-insertion site.
Summary for 4B9L
| Entry DOI | 10.2210/pdb4b9l/pdb |
| Related | 2XO7 2XY5 2XY6 2XY7 2Y1I 2Y1J 4B9M 4B9N |
| Related PRD ID | PRD_900003 |
| Descriptor | DNA POLYMERASE I, 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*TP)-3', 5'-D(*CP*AP*GP*FAX*AP*GP*AP*GP*TP*CP*AP*GP*GP*CP*TP)-3', ... (7 entities in total) |
| Functional Keywords | transferase-dna complex, oxidative dna lesion, dna damage, trans lesion synthesis, replication, transferase/dna |
| Biological source | GEOBACILLUS STEAROTHERMOPHILUS More |
| Total number of polymer chains | 3 |
| Total formula weight | 78852.49 |
| Authors | Gehrke, T.H.,Lischke, U.,Arnold, S.,Schneider, S.,Carell, T. (deposition date: 2012-09-05, release date: 2013-04-17, Last modification date: 2023-12-20) |
| Primary citation | Gehrke, T.H.,Lischke, U.,Gasteiger, K.L.,Schneider, S.,Arnold, S.,Muller, H.C.,Stephenson, D.S.,Zipse, H.,Carell, T. Unexpected Non-Hoogsteen-Based Mutagenicity Mechanism of Fapy-DNA Lesions. Nat.Chem.Biol., 9:455-, 2013 Cited by PubMed: 23685671DOI: 10.1038/NCHEMBIO.1254 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report
