4B86

Crystal structure of the MSL1-MSL2 complex (3.5A)

Summary for 4B86

• Entry DOI: 10.2210/pdb4b86/pdb
• Related: 4B7Y
• Descriptor: MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 2 HOMOLOG, ZINC ION (3 entities in total)
• Functional Keywords: gene regulation, dosage compensation, chromatin
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: Q68DK7
• Total number of polymer chains: 12
• Total formula weight: 120744.14

Authors

Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J. (deposition date: 2012-08-24, release date: 2013-02-06)

• Primary citation: Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J.; Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila.; Mol.Cell, 48:587-, 2012; PubMed: 23084835; DOI: 10.1016/J.MOLCEL.2012.09.014

Experimental method

X-RAY DIFFRACTION (3.5 Å)