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4B7R

H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis

Summary for 4B7R
Entry DOI10.2210/pdb4b7r/pdb
Related4B7J 4B7M 4B7N 4B7Q
DescriptorNEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
Functional Keywordshydrolase, neuraminidase inhibitor, nai, nais, zanamivir, resistance, antiviral resistance
Biological sourceINFLUENZA A VIRUS (A/CALIFORNIA/07/2009(H1N1))
Total number of polymer chains4
Total formula weight176052.35
Authors
Primary citationVan Der Vries, E.,Collins, P.J.,Vachieri, S.G.,Xiong, X.,Liu, J.,Walker, P.A.,Haire, L.F.,Hay, A.J.,Schutten, M.,Osterhaus, A.D.M.E.,Martin, S.R.,Boucher, C.A.B.,Skehel, J.J.,Gamblin, S.J.
H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8:2914-, 2012
Cited by
PubMed: 23028314
DOI: 10.1371/JOURNAL.PPAT.1002914
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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