4B79

THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.

Summary for 4B79

• Entry DOI: 10.2210/pdb4b79/pdb
• Related: 4AVY
• Descriptor: PROBABLE SHORT-CHAIN DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: oxidoreductase, infectious disease, structure-based inhibitor design
• Biological source: PSEUDOMONAS AERUGINOSA PAO1
• Total number of polymer chains: 2
• Total formula weight: 52737.45

Authors

Moynie, L.,McMahon, S.A.,Alphey, M.S.,Liu, H.,Duthie, F.,Naismith, J.H. (deposition date: 2012-08-16, release date: 2012-08-29, Last modification date: 2023-12-20)

• Primary citation: Moynie, L.,Schnell, R.,Mcmahon, S.A.,Sandalova, T.,Boulkerou, W.A.,Schmidberger, J.W.,Alphey, M.S.,Cukier, C.,Duthie, F.,Kopec, J.,Liu, H.,Jacewicz, A.,Hunter, W.N.,Naismith, J.H.,Schneider, G.; The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery; Acta Crystallogr.,Sect.F, 69:25-, 2013; PubMed: 23295481; DOI: 10.1107/S1744309112044739

Experimental method

X-RAY DIFFRACTION (1.98 Å)