4B56

Structure of ectonucleotide pyrophosphatase-phosphodiesterase-1 (NPP1)

Summary for 4B56

Entry DOI	10.2210/pdb4b56/pdb
Descriptor	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase
Biological source	MUS MUSCULUS (MOUSE)
Total number of polymer chains	2
Total formula weight	192777.26
Authors	Jansen, S.,Perrakis, A.,Ulens, C.,Winkler, C.,Andries, M.,Joosten, R.P.,Van Acker, M.,Luyten, F.P.,Moolenaar, W.H.,Bollen, M. (deposition date: 2012-08-02, release date: 2012-09-19, Last modification date: 2023-12-20)
Primary citation	Jansen, S.,Perrakis, A.,Ulens, C.,Winkler, C.,Andries, M.,Joosten, R.P.,Van Acker, M.,Luyten, F.P.,Moolenaar, W.H.,Bollen, M. Structure of Npp1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification. Structure, 20:1948-, 2012 Cited by PubMed: 23041369 DOI: 10.1016/J.STR.2012.09.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation