4B0P

Crystal structure of soman-aged human butyrylcholinesterase in complex with methyl 2-(pentafluorobenzyloxyimino)pyridinium

Summary for 4B0P

Entry DOI	10.2210/pdb4b0p/pdb
Related	1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQF 2XQG 2XQI 2XQJ 2XQK 2Y1K 4AQD 4AXB 4B0O
Descriptor	CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... (10 entities in total)
Functional Keywords	hydrolase, aging
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62596.93
Authors	Wandhammer, M.,de Koning, M.,van Grol, M.,Noort, D.,Goeldner, M.,Nachon, F. (deposition date: 2012-07-04, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Wandhammer, M.,De Koning, M.,Van Grol, M.,Loiodice, M.,Saurel, L.,Noort, D.,Goeldner, M.,Nachon, F. A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase Chem.Biol.Interact, 203:19-, 2013 Cited by PubMed: 22922115 DOI: 10.1016/J.CBI.2012.08.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation