4AYP

Structure of The GH47 processing alpha-1,2-mannosidase from Caulobacter strain K31 in complex with thiomannobioside

Summary for 4AYP

Entry DOI	10.2210/pdb4ayp/pdb
Related	4AYO 4AYQ 4AYR
Related PRD ID	PRD_900033
Descriptor	MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE, alpha-D-mannopyranose-(1-2)-methyl 2-thio-alpha-D-mannopyranoside, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, glycoside hydrolase, gh47, cazy, enzyme-carbohydrate interaction, mannose, glycosidase inhibition, quantum mechanics
Biological source	CAULOBACTER SP.
Total number of polymer chains	1
Total formula weight	51022.21
Authors	Thompson, A.J.,Dabin, J.,Iglesias-Fernandez, J.,Iglesias-Fernandez, A.,Dinev, Z.,Williams, S.J.,Siriwardena, A.,Moreland, C.,Hu, T.C.,Smith, D.K.,Gilbert, H.J.,Rovira, C.,Davies, G.J. (deposition date: 2012-06-21, release date: 2013-01-30, Last modification date: 2020-07-29)
Primary citation	Thompson, A.J.,Dabin, J.,Iglesias-Fernandez, J.,Ardevol, A.,Dinev, Z.,Williams, S.J.,Bande, O.,Siriwardena, A.,Moreland, C.,Hu, T.C.,Smith, D.K.,Gilbert, H.J.,Rovira, C.,Davies, G.J. The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach. Angew.Chem.Int.Ed.Engl., 51:10997-, 2012 Cited by PubMed: 23012075 DOI: 10.1002/ANIE.201205338 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.85 Å)

Structure validation