4AYC

RNF8 RING domain structure

Summary for 4AYC

• Entry DOI: 10.2210/pdb4ayc/pdb
• Related: 2CSW
• Descriptor: E3 UBIQUITIN-PROTEIN LIGASE RNF8, SULFATE ION, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE, ... (8 entities in total)
• Functional Keywords: ligase, dna damage, k63 chains
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: O76064 O76064
• Total number of polymer chains: 2
• Total formula weight: 34261.59

Authors

Mattiroli, F.,Vissers, J.H.A.,Van Dijk, W.J.,Ikpa, P.,Citterio, E.,Vermeulen, W.,Marteijn, J.A.,Sixma, T.K. (deposition date: 2012-06-20, release date: 2012-09-26)

• Primary citation: Mattiroli, F.,Vissers, J.H.A.,Van Dijk, W.J.,Ikpa, P.,Citterio, E.,Vermeulen, W.,Marteijn, J.A.,Sixma, T.K.; Rnf168 Ubiquitinates K13-15 on H2A/H2Ax to Drive DNA Damage Signaling; Cell(Cambridge,Mass.), 150:1182-, 2012; PubMed: 22980979; DOI: 10.1016/J.CELL.2012.08.005

Experimental method

X-RAY DIFFRACTION (1.9 Å)