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4AVK

Structure of trigonal FimH lectin domain crystal soaked with an alpha- D-mannoside O-linked to propynyl pyridine at 2.4A resolution

Summary for 4AVK
Entry DOI10.2210/pdb4avk/pdb
Related4ATT 4AUJ 4AUU 4AUY 4AV0 4AV4 4AV5 4AVH 4AVI 4AVJ
DescriptorFIMH, 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordscell adhesion, bacterial adhesin, type 1 fimbriae, urinary tract infection, variable immunoglobulin fold
Biological sourceESCHERICHIA COLI
Total number of polymer chains2
Total formula weight34925.87
Authors
Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. (deposition date: 2012-05-26, release date: 2012-06-27, Last modification date: 2023-12-20)
Primary citationWellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J.
The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.
Biochemistry, 51:4790-, 2012
Cited by
PubMed: 22657089
DOI: 10.1021/BI300251R
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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