4APO

AIP TPR domain in complex with human Tomm20 peptide

Summary for 4APO

Entry DOI	10.2210/pdb4apo/pdb
Related	4AIF
Descriptor	AH RECEPTOR-INTERACTING PROTEIN, MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG, DODECAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	signaling protein-peptide complex, aryl hydrocarbon receptor, signaling protein/peptide
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm: O00170 Mitochondrion outer membrane; Single-pass membrane protein (Potential): Q15388
Total number of polymer chains	4
Total formula weight	39943.07
Authors	Morgan, R.M.L.,Roe, S.M.,Pearl, L.H.,Prodromou, C. (deposition date: 2012-04-04, release date: 2013-01-23, Last modification date: 2023-12-20)
Primary citation	Morgan, R.M.,Hernandez-Ramirez, L.C.,Trivellin, G.,Zhou, L.,Roe, S.M.,Korbonits, M.,Prodromou, C. Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition. Plos One, 7:53339-, 2012 Cited by PubMed: 23300914 DOI: 10.1371/JOURNAL.PONE.0053339 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.895 Å)

Structure validation