4AOT

Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A

Summary for 4AOT

• Entry DOI: 10.2210/pdb4aot/pdb
• Related: 2J7T 3ZZ2
• Descriptor: Serine/threonine-protein kinase 10, CHLORIDE ION, 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea, ... (4 entities in total)
• Functional Keywords: transferase, stk10, lok
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 70067.42

Authors

Elkins, J.M.,Salah, E.,Szklarz, M.,Canning, P.,von Delft, F.,Yue, W.,Liu, Y.,Bountra, C.,Arrowsmith, C.,Edwards, A.,Knapp, S. (deposition date: 2012-03-29, release date: 2012-04-11, Last modification date: 2023-12-20)

• Primary citation: Elkins, J.M.,Salah, E.,Szklarz, M.,Canning, P.,von Delft, F.,Yue, W.,Liu, Y.,Bountra, C.,Arrowsmith, C.,Edwards, A.,Knapp, S.; Crystal Structure of Human Serine Threonine Kinase-10 (Lok) Bound to Gw830263A; To be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)