4AJ0
Crystallographic structure of an amyloidogenic variant, 3rCW, of the germinal line lambda 3
Summary for 4AJ0
| Entry DOI | 10.2210/pdb4aj0/pdb |
| Related | 4AIX 4AIZ |
| Descriptor | GERMINAL LINE LAMBDA 3 3RCW VARIANT, 2-(2-METHOXYETHOXY)ETHANOL, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | immune system, amyloidosis |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 4 |
| Total formula weight | 45452.75 |
| Authors | Villalba, M.I.,Luna, O.D.,Rudino-Pinera, E.,Sanchez, R.,Sanchez-Lopez, R.,Rojas-Trejo, S.,Olamendi-Portugal, T.,Fernandez-Velasco, D.A.,Becerril, B. (deposition date: 2012-02-15, release date: 2013-02-27, Last modification date: 2023-12-20) |
| Primary citation | Villalba, M.I.,Canul-Tec, J.C.,Luna-Martinez, O.D.,Sanchez-Alcala, R.,Olamendi-Portugal, T.,Rudino-Pinera, E.,Rojas, S.,Sanchez-Lopez, R.,Fernandez-Velasco, D.A.,Becerril, B. Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains. J.Biol.Chem., 290:2577-, 2015 Cited by PubMed: 25505244DOI: 10.1074/JBC.M114.629550 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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