459D
DNA MINOR-GROOVE RECOGNITION OF A TRIS-BENZIMIDAZOLE DRUG
Summary for 459D
Entry DOI | 10.2210/pdb459d/pdb |
Descriptor | DNA (5'-D(*CP*GP*(CBR)P*AP*TP*AP*TP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*AP*TP*GP*CP*G)-3'), 2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE, ... (4 entities in total) |
Functional Keywords | minor groove binding, b-dna, complexed with tris-benzimidazole, deoxyribonucleic acid, dna |
Total number of polymer chains | 2 |
Total formula weight | 7945.33 |
Authors | Aymami, J.,Nunn, C.M.,Neidle, S. (deposition date: 1999-03-10, release date: 1999-06-28, Last modification date: 2023-12-27) |
Primary citation | Aymami, J.,Nunn, C.M.,Neidle, S. DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand. Nucleic Acids Res., 27:2691-2698, 1999 Cited by PubMed: 10373586DOI: 10.1093/nar/27.13.2691 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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