3ZP5

Crystal structure of the DNA binding ETS domain of the human protein FEV in complex with DNA

Summary for 3ZP5

• Entry DOI: 10.2210/pdb3zp5/pdb
• Descriptor: PROTEIN FEV, 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3', 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', ... (4 entities in total)
• Functional Keywords: transcription-dna complex, transcription/dna
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus : Q99581
• Total number of polymer chains: 3
• Total formula weight: 17903.44

Authors

Newman, J.A.,Cooper, C.D.O.,Krojer, T.,Shrestha, L.,Allerston, C.K.,Vollmar, M.,Arrowsmith, C.H.,Burgess-Brown, N.,Edwards, A.,von Delft, F.,Gileadi, O. (deposition date: 2013-02-26, release date: 2013-03-06, Last modification date: 2023-12-20)

• Primary citation: Cooper, C.D.O.,Newman, J.A.,Aitkenhead, H.,Allerston, C.K.,Gileadi, O.; Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.; J.Biol.Chem., 290:13692-, 2015; PubMed: 25866208; DOI: 10.1074/JBC.M115.646737

Experimental method

X-RAY DIFFRACTION (2 Å)