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3ZNS

HDAC7 bound with TFMO inhibitor tmp942

Summary for 3ZNS
Entry DOI10.2210/pdb3zns/pdb
Related3ZNR
DescriptorHISTONE DEACETYLASE 7, ZINC ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywordshydrolase, zbg, mbg
Biological sourceHOMO SAPIENS
Cellular locationNucleus: Q8WUI4
Total number of polymer chains3
Total formula weight138764.74
Authors
Lobera, M.,Madauss, K.P.,Pohlhaus, D.T.,Trump, R.P.,Nolan, M.A. (deposition date: 2013-02-15, release date: 2013-03-27, Last modification date: 2013-05-01)
Primary citationLobera, M.,Madauss, K.P.,Pohlhaus, D.T.,Wright, Q.G.,Trocha, M.,Schmidt, D.R.,Baloglu, E.,Trump, R.P.,Head, M.S.,Hofmann, G.A.,Murray-Thompson, M.,Schwartz, B.,Chakravorty, S.,Wu, Z.,Mander, P.K.,Kruidenier, L.,Reid, R.A.,Burkhart, W.,Turunen, B.J.,Rong, J.X.,Wagner, C.,Moyer, M.B.,Wells, C.,Hong, X.,Moore, J.T.,Williams, J.D.,Soler, D.,Ghosh, S.,Nolan, M.A.
Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9:319-, 2013
Cited by
PubMed: 23524983
DOI: 10.1038/NCHEMBIO.1223
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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