3ZLV
Crystal structure of mouse acetylcholinesterase in complex with tabun and HI-6
Summary for 3ZLV
Entry DOI | 10.2210/pdb3zlv/pdb |
Related | 3ZLT 3ZLU |
Descriptor | ACETYLCHOLINESTERASE, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, CARBONATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase, rvx, russian vx, cyclosarin |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Cell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836 |
Total number of polymer chains | 2 |
Total formula weight | 121310.75 |
Authors | Artursson, E.,Andersson, P.O.,Akfur, C.,Linusson, A.,Borjegren, S.,Ekstrom, F. (deposition date: 2013-02-04, release date: 2013-03-27, Last modification date: 2023-12-20) |
Primary citation | Artursson, E.,Andersson, P.O.,Akfur, C.,Linusson, A.,Borjegren, S.,Ekstrom, F. Catalytic-Site Conformational Equilibrium in Nerve-Agent Adducts of Acetylcholinesterase; Possible Implications for the Hi-6 Antidote Substrate Specificity. Biochem.Pharmacol., 85:1389-, 2013 Cited by PubMed: 23376121DOI: 10.1016/J.BCP.2013.01.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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